SKU: WP11157 Categories: ,

AR-α1D Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11157-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetAR-α1D
ReactivityHuman, Mouse, Rat
ApplicationsIHC, IF, ELISA
MW(Calculated)60kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ADRA1D. AA range:451-500
SpecificityAR-α1D Polyclonal Antibody detects endogenous levels of AR-α1D protein.
Gene NameADRA1D
Protein NameAlpha-1D adrenergic receptor
Other NameADRA1D; / ADRA1A; / Alpha-1D adrenergic receptor; / Alpha-1A adrenergic receptor; / Alpha-1D adrenoreceptor; / Alpha-1D adrenoceptor; / Alpha-adrenergic receptor 1a
SpeciesHuman
Gene ID146
UniprotP25100,
Species.1Mouse
Gene ID.1
Uniprot.1P97714
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue ExpressionHippocampus,Placenta,Prostate,
Signaling_pathwayOrganismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes;Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction;Environmental Information Processing >> Signal transduction >> Calcium signaling pathway;Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
Research Areas>>Calcium signaling pathway; / >>cGMP-PKG signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Adrenergic signaling in cardiomyocytes; / >>Vascular smooth muscle contraction; / >>Salivary secretion
FunctionFunction:This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Please login to post questions
Back to Top
Product has been added to your cart