ARF5 Polyclonal Antibody
Ucallm_WP0845-50
Price range: $268.00 through $328.00
Product details
Background:
ADP ribosylation factor 5(ARF5) Homo sapiens This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010],
Specifications
| Size | 50μL/100μL |
| Target | ARF5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 19kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 40-120 |
| Specificity | ARF5 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ARF5 |
| Protein Name | ADP-ribosylation factor 5 |
| Other Name | |
| Species | Human |
| Gene ID | 381 |
| Uniprot | P84085, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P84084, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P84083 |
| Cellular Localization | Golgi apparatus . Cytoplasm, perinuclear region . Membrane; Lipid-anchor . Golgi apparatus, trans-Golgi network membrane; Lipid-anchor . |
| Tissue Expression | Brain,Lung,Skin,Tongue, |
| Signaling_pathway | |
| Research Areas | >>Endocytosis |
| Function | Function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.,similarity:Belongs to the small GTPase superfamily.,similarity:Belongs to the small GTPase superfamily. Arf family.,subunit:Binds ASAP2., |
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