Price range: $268.00 through $328.00
Background:
This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014],
| Target | ARH40 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 167kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARH40 AA range: 1261-1311 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ARH40 at Human/Mouse |
| Gene Name | ARHGEF40 SOLO |
| Protein Name | ARH40 |
| Other Name | |
| Species | Human |
| Gene ID-1 | 55701 |
| Uniprot | Q8TER5, |
| Species.1 | Mouse |
| Gene ID-2 | 268739 |
| Uniprot.1 | Q3UPH7 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014], |
| Cellular Localization | Cytoplasm . Concentrated in the perinuclear region. |
| Tissue Expression | Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May act as a guanine nucleotide exchange factor (GEF).,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,subcellular location:Concentrated in the perinuclear region.,tissue specificity:Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level)., |
| RRID |
