SKU: WP3491 Categories: ,

ARI3B rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3491-100
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Product details

Background:

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetARI3B
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)
MW(Observed)60kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ARI3B AA range: 459-509
SpecificityThis antibody detects endogenous levels of ARI3B at Human/Mouse
Gene NameARID3B BDP DRIL2
Protein NameARI3B
Other NameAT-rich interactive domain-containing protein 3B; / ARID domain-containing protein 3B; / Bright and dead ringer protein; / Bright-like protein
SpeciesHuman
Gene ID10620
UniprotQ8IVW6,
Species.1Mouse
Gene ID.156380
Uniprot.1Q9Z1N7
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionExpressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K-562 erythrocytic leukemia cell line (at protein level).
Signaling_pathway
Research Areas
FunctionFunction:Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.,similarity:Contains 1 ARID domain.,subunit:Heterodimer with ARID3A. Interacts with unphosphorylated RB1.,tissue specificity:Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level).,
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