ARI3B rabbit pAb
Ucallm_WP3491-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ARI3B |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARI3B AA range: 459-509 |
| Specificity | This antibody detects endogenous levels of ARI3B at Human/Mouse |
| Gene Name | ARID3B BDP DRIL2 |
| Protein Name | ARI3B |
| Other Name | AT-rich interactive domain-containing protein 3B; / ARID domain-containing protein 3B; / Bright and dead ringer protein; / Bright-like protein |
| Species | Human |
| Gene ID | 10620 |
| Uniprot | Q8IVW6, |
| Species.1 | Mouse |
| Gene ID.1 | 56380 |
| Uniprot.1 | Q9Z1N7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K-562 erythrocytic leukemia cell line (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.,similarity:Contains 1 ARID domain.,subunit:Heterodimer with ARID3A. Interacts with unphosphorylated RB1.,tissue specificity:Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level)., |
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