Product details
Background:
ARL13B rabbit pAb
Ucallm_WP5952-50
Price range: $268.00 through $328.00
Specifications
| Target | ARL13B |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 47kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARL13B |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ARL13B at Human, Mouse |
| Gene Name | ARL13B ARL2L1 |
| Protein Name | ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 200894 |
| Uniprot | Q3SXY8, |
| Species.1 | Mouse |
| Gene ID-2 | 68146 |
| Uniprot.1 | Q640N2 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Cell projection, cilium membrane; Lipid-anchor . Cell projection, cilium . Associates to the cilium membrane via palmitoylation. Localizes to proximal ciliary membranes, to an inversin-like subciliary membrane compartment, excluding the transition zone. |
| Tissue Expression | Expressed in the developing brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidence is required to confirm these data. |
| RRID |
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