Product details
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ARL4C rabbit pAb
Ucallm_WP6196-50
Price range: $268.00 through $328.00
Specifications
| Target | ARL4C |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 21kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARL4C |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ARL4C at Human, Mouse |
| Gene Name | ARL4C ARL7 |
| Protein Name | ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 10123 |
| Uniprot | P56559, |
| Species.1 | Mouse |
| Gene ID-2 | 320982 |
| Uniprot.1 | P61208 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Cell projection, filopodium. Cell membrane. Cytoplasm. |
| Tissue Expression | Expressed in several tumor cell lines (at protein level). Expressed in lung, brain, leukocytes and placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process. |
| RRID |
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