Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human Arp5/ACTR5
Specificity
This antibody detects endogenous levels of Arp5/ACTR5 at Human, Mouse
Gene Name
ACTR5 ARP5
Protein Name
Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16)
Other Name
Species
Human
Gene ID
79913
Uniprot
Q9H9F9,
Species.1
Mouse
Gene ID.1
109275
Uniprot.1
Q80US4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Cytoplasm . Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses (PubMed:18163988).
Tissue Expression
Signaling_pathway
Genetic Information Processing >> Chromosome >> ATP-dependent chromatin remodeling
Research Areas
Function
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.