Product details
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ASL rabbit pAb
Ucallm_WP6807-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ASL |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 51kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ASL |
| Specificity | This antibody detects endogenous levels of ASL at Human, Mouse,Rat |
| Gene Name | ASL |
| Protein Name | Argininosuccinate lyase (ASAL) (Arginosuccinase) |
| Other Name | |
| Species | Human |
| Gene ID | 435 |
| Uniprot | P04424, |
| Species.1 | Mouse |
| Gene ID.1 | 109900 |
| Uniprot.1 | Q91YI0, |
| Species.2 | Rat |
| Gene ID.2 | 59085 |
| Uniprot.2 | P20673 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the reversible cleavage of L-argininosuccinate to fumarate and L-arginine, an intermediate step reaction in the urea cycle mostly providing for hepatic nitrogen detoxification into excretable urea as well as de novo L-arginine synthesis in nonhepatic tissues . Essential regulator of intracellular and extracellular L-arginine pools. As part of citrulline-nitric oxide cycle, forms tissue-specific multiprotein complexes with argininosuccinate synthase ASS1, transport protein SLC7A1 and nitric oxide synthase NOS1, NOS2 or NOS3, allowing for cell-autonomous L-arginine synthesis while channeling extracellular L-arginine to nitric oxide synthesis pathway . |
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