Name: ASZ1 rabbit pAb
SKU: WP7049
Price: 268 USD
Availability: InStock

ASZ1 rabbit pAb

Ucallm_WP7049-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP7049-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	ASZ1
Reactivity	Human, Mouse
Applications	WB
MW(Calculated)	52kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human ASZ1
Specificity	This antibody detects endogenous levels of ASZ1 at Human, Mouse
Gene Name	ASZ1 ALP1 ANKL1 C7orf7 GASZ
Protein Name	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Ankyrin-like protein 1) (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein)
Other Name
Species	Human
Gene ID	136991
Uniprot	Q8WWH4,
Species.1	Mouse
Gene ID.1	74068
Uniprot.1	Q8VD46
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm . Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity). .
Tissue Expression	Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
Signaling_pathway
Research Areas
Function	Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).