Product details
Background:
ATAD2 rabbit pAb
Ucallm_WP6692-50
Price range: $268.00 through $328.00
Specifications
| Target | ATAD2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 153kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATAD2 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ATAD2 at Human, Mouse |
| Gene Name | ATAD2 L16 PRO2000 |
| Protein Name | ATPase family AAA domain-containing protein 2 (AAA nuclear coregulator cancer-associated protein) (ANCCA) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 29028 |
| Uniprot | Q6PL18, |
| Species.1 | Mouse |
| Gene ID-2 | 70472 |
| Uniprot.1 | Q8CDM1 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. |
| Signaling_pathway | |
| Research Areas | |
| Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |
| RRID |
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