Product details
Background:
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ATAD3A/B rabbit pAb
Ucallm_WP6314-50
Price range: $268.00 through $328.00
Specifications
| Target | ATAD3B |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 71kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATAD3A/B |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ATAD3A/B at Human |
| Gene Name | ATAD3B KIAA1273 TOB3 |
| Protein Name | ATPase family AAA domain-containing protein 3B (AAA-TOB3) |
| Other Name | |
| Species | Human |
| Gene ID-1 | 83858 |
| Uniprot | Q5T9A4 |
| Species.1 | |
| Gene ID-2 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Mitochondrion inner membrane; Peripheral membrane protein . Has been found to co-purify with nucleoids (PubMed:22453275). Since it does not face the mitochondrial matrix, the association with nucleoids could be mediated by ATAD3A. . |
| Tissue Expression | Tends to be down-regulated in differentiated cells and re-expressed in pluripotent stem cells or cancer cells (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. |
| RRID |
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