Name: ATF-5 Polyclonal Antibody
SKU: WP11186
Price: 268 USD
Availability: InStock

ATF-5 Polyclonal Antibody

Ucallm_WP11186-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP11186-100

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Product details

Background:

function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5′-GTGACGT[AC][AG]-3′), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4., similarity:Belongs to the bZIP family., similarity:Contains 1 bZIP domain., subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,

Specifications

Size	50μL/100μL
Target	ATF5
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	31kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human ATF5. AA range:221-270
Specificity	ATF-5 Polyclonal Antibody detects endogenous levels of ATF-5 protein.
Gene Name	ATF5
Protein Name	Cyclic AMP-dependent transcription factor ATF-5
Other Name	ATF5; / ATFX; / Cyclic AMP-dependent transcription factor ATF-5; / cAMP-dependent transcription factor ATF-5; / Activating transcription factor 5; / Transcription factor ATFx
Species	Human
Gene ID	22809
Uniprot	Q9Y2D1,
Species.1	Mouse
Gene ID.1	107503
Uniprot.1	O70191,
Species.2	Rat
Gene ID.2	282840
Uniprot.2	Q6P788
Cellular Localization	Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. .
Tissue Expression	Widely expressed with higher expression levels in liver.
Signaling_pathway
Research Areas
Function	Function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,