ATG101 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ATG101 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 24kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATG101 |
| Specificity | This antibody detects endogenous levels of ATG101 at Human, Mouse,Rat |
| Gene Name | ATG101 C12orf44 PP894 |
| Protein Name | Autophagy-related protein 101 |
| Other Name | |
| Species | Human |
| Gene ID | 60673 |
| Uniprot | Q9BSB4, |
| Species.1 | Mouse |
| Gene ID.1 | 68118 |
| Uniprot.1 | Q9D8Z6, |
| Species.2 | Rat |
| Gene ID.2 | 300240 |
| Uniprot.2 | Q6AY69 |
| Cellular Localization | Cytoplasm . Preautophagosomal structure . Under starvation conditions, it is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal;Organismal Systems >> Aging >> Longevity regulating pathway;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases |
| Research Areas | |
| Function | Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation. |
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