Product details
Background:
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq, Jul 2008],
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ATOH1 rabbit pAb
Ucallm_WP3454-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ATOH1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATOH1 AA range: 38-88 |
| Specificity | This antibody detects endogenous levels of ATOH1 at Human/Mouse |
| Gene Name | ATOH1 ATH1 BHLHA14 |
| Protein Name | ATOH1 |
| Other Name | Protein atonal homolog 1; / Class A basic helix-loop-helix protein 14; / bHLHa14; / Helix-loop-helix protein hATH-1; / hATH1 |
| Species | Human |
| Gene ID | 474 |
| Uniprot | Q92858, |
| Species.1 | Mouse |
| Gene ID.1 | 11921 |
| Uniprot.1 | P48985 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | PCR rescued clones, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. May play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein., |
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