Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ATP11B
Specificity
This antibody detects endogenous levels of ATP11B at Human
Gene Name
ATP11B ATPIF ATPIR KIAA0956
Protein Name
Probable phospholipid-transporting ATPase IF (ATPase IR) (ATPase class VI type 11B)
Other Name
Species
Human
Gene ID
23200
Uniprot
Q9Y2G3
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Recycling endosome membrane; Multi-pass membrane protein. Early endosome . Endoplasmic reticulum . Golgi apparatus, trans-Golgi network . Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B (PubMed:21914794). In the presence of TMEM30A, mainly located in recycling endosomes (PubMed:21914794). .
Tissue Expression
Signaling_pathway
Research Areas
Function
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes . May contribute to the maintenance of membrane lipid asymmetry in endosome compartment .