SKU: WP6771 Categories: ,

ATP11B rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6771-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetATP11B
ReactivityHuman
ApplicationsWB
MW(Calculated)129kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ATP11B
SpecificityThis antibody detects endogenous levels of ATP11B at Human
Gene NameATP11B ATPIF ATPIR KIAA0956
Protein NameProbable phospholipid-transporting ATPase IF (ATPase IR) (ATPase class VI type 11B)
Other Name
SpeciesHuman
Gene ID23200
UniprotQ9Y2G3
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationRecycling endosome membrane; Multi-pass membrane protein. Early endosome . Endoplasmic reticulum . Golgi apparatus, trans-Golgi network . Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B (PubMed:21914794). In the presence of TMEM30A, mainly located in recycling endosomes (PubMed:21914794). .
Tissue Expression
Signaling_pathway
Research Areas
FunctionCatalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes . May contribute to the maintenance of membrane lipid asymmetry in endosome compartment .
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