Product details
Background:
- Please choose product options by visiting IFNA4 Polyclonal Antibody.
ATP9A rabbit pAb
Ucallm_WP8902-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ATP9A |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 115kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATP9A |
| Specificity | This antibody detects endogenous levels of ATP9A at Human, Mouse |
| Gene Name | ATP9A ATPIIA KIAA0611 |
| Protein Name | Probable phospholipid-transporting ATPase IIA (ATPase class II type 9A) |
| Other Name | |
| Species | Human |
| Gene ID | 10079 |
| Uniprot | O75110, |
| Species.1 | Mouse |
| Gene ID.1 | 11981 |
| Uniprot.1 | O70228 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Early endosome membrane; Multi-pass membrane protein . Recycling endosome membrane; Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein . Cell membrane; Multi-pass membrane protein. Efficient exit from the endoplasmic reticulum does not require TMEM30A, nor TMEM30B (PubMed:21914794). Transiently expressed in the plasma membrane (PubMed:30947313). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays a role in regulating membrane trafficking of cargo proteins, namely endosome to plasma membrane recycling and endosome to trans-Golgi network retrograde transport . In complex with MON2 and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS, a transporter of Wnt morphogens in developing tissues. Participates in the formation of endosomal carriers that direct WLS trafficking back to Golgi, away from lysosomal degradation . Appears to be implicated in intercellular communication by negatively regulating the release of exosomes . The flippase activity towards membrane lipids and its role in membrane asymmetry remains to be proved . |
Please login to post questions
Related products
