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U-Blot® Bovine early pregnancy-associated glycoprotein-2 (PAG-2protein)Mouse mAb
$1,880.00$1,880.00× -
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ATX3L rabbit pAb
Product details
Background:
This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. [provided by RefSeq, Sep 2011],
Specifications
| Size | 50μL/100μL |
| Target | ATX3L |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATX3L AA range: 99-149 |
| Specificity | This antibody detects endogenous levels of ATX3L at Human |
| Gene Name | ATXN3L ATX3L MJDL |
| Protein Name | ATX3L |
| Other Name | Putative ataxin-3-like protein; / Machado-Joseph disease protein 1-like |
| Species | Human |
| Gene ID | 92552 |
| Uniprot | Q9H3M9 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Testis, |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum |
| Research Areas | >>Protein processing in endoplasmic reticulum; / >>Spinocerebellar ataxia; / >>Pathways of neurodegeneration - multiple diseases |
| Function | Caution:Could be the product of a pseudogene. Suggested by the absence of intron.,Function:May bind to histones and regulate transcription. May act as a deubiquitinating enzyme.,similarity:Contains 1 Josephin domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats., |
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