Price range: $268.00 through $328.00
Background:
This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012],
| Size | 50μL/100μL |
| Target | B2L13 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 53kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | B2L13 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | BCL2L13 MIL1 CD003 |
| Protein Name | Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1) |
| Other Name | |
| Species | Human |
| Gene ID | 23786 |
| Uniprot | Q9BXK5, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P59017 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 2]: Mitochondrion membrane; Single-pass membrane protein . Nucleus .; [Isoform 1]: Nucleus . |
| Tissue Expression | Ubiquitous, with the highest levels of expression in heart, placenta and pancreas. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Mitophagy - animal |
| Research Areas | >>Mitophagy - animal; / >>Legionellosis |
| Function | Alternative products:Experimental confirmation may be lacking for some isoforms,Function:May promote the activation of caspase-3 and apoptosis.,similarity:Belongs to the Bcl-2 family.,subunit:Monomer.,tissue specificity:Ubiquitous, with the highest levels of expression in heart, placenta and pancreas., |
