B3GNT7 rabbit pAb
Ucallm_WP8662-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | B3GNT7 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 44kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human B3GNT7 |
| Specificity | This antibody detects endogenous levels of B3GNT7 at Human, Mouse,Rat |
| Gene Name | B3GNT7 |
| Protein Name | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 (BGnT-7) (Beta-1,3-Gn-T7) (Beta-1,3-N-acetylglucosaminyltransferase 7) (Beta3Gn-T7) (EC 2.4.1.-) |
| Other Name | |
| Species | Human |
| Gene ID | 93010 |
| Uniprot | Q8NFL0, |
| Species.1 | Mouse |
| Gene ID.1 | 227327 |
| Uniprot.1 | Q8K0J2, |
| Species.2 | Rat |
| Gene ID.2 | 316583 |
| Uniprot.2 | Q66H69 |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein . |
| Tissue Expression | Expressed in corneal epithelial cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer . Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (By similarity). May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (By similarity). |
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