Price range: $268.00 through $328.00
Background:
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | BAI-3 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 171kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BAI3. AA range:211-260 |
| Specificity | BAI-3 Polyclonal Antibody detects endogenous levels of BAI-3 protein. |
| Gene Name | BAI3 |
| Protein Name | Brain-specific angiogenesis inhibitor 3 |
| Other Name | BAI3; / KIAA0550; / Brain-specific angiogenesis inhibitor 3 |
| Species | Human |
| Gene ID | 577 |
| Uniprot | O60242, |
| Species.1 | Mouse |
| Gene ID.1 | 210933 |
| Uniprot.1 | Q80ZF8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Might be involved in angiogenesis inhibition and suppression of glioblastoma.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 4 TSP type-1 domains.,tissue specificity:Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines., |
