Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human BANP
Specificity
This antibody detects endogenous levels of BANP at Human, Mouse
Gene Name
BANP BEND1 SMAR1
Protein Name
Protein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein)
Other Name
Species
Human
Gene ID
54971
Uniprot
Q8N9N5,
Species.1
Mouse
Gene ID.1
53325
Uniprot.1
Q8VBU8
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus .
Tissue Expression
Down-regulated in breast cancer cell lines.
Signaling_pathway
Research Areas
Function
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest (By similarity).