SKU: WP6902 Categories: ,

BANP rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6902-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetBANP
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)57kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human BANP
SpecificityThis antibody detects endogenous levels of BANP at Human, Mouse
Gene NameBANP BEND1 SMAR1
Protein NameProtein BANP (BEN domain-containing protein 1) (Btg3-associated nuclear protein) (Scaffold/matrix-associated region-1-binding protein)
Other Name
SpeciesHuman
Gene ID54971
UniprotQ8N9N5,
Species.1Mouse
Gene ID.153325
Uniprot.1Q8VBU8
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionDown-regulated in breast cancer cell lines.
Signaling_pathway
Research Areas
FunctionControls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest (By similarity).
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