BCA3 Polyclonal Antibody
Product details
Background:
This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
Specifications
| Size | 50μL/100μL |
| Target | BCA3 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 26kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BCA3. AA range:111-160 |
| Specificity | BCA3 Polyclonal Antibody detects endogenous levels of BCA3 protein. |
| Gene Name | AKIP1 |
| Protein Name | A-kinase-interacting protein 1 |
| Other Name | AKIP1; / BCA3; / C11orf17; / A-kinase-interacting protein 1; / Breast cancer-associated gene 3 protein; / PKA-interacting protein; / Proline-rich protein BCA3 |
| Species | Human |
| Gene ID | 56672 |
| Uniprot | Q9NQ31, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9JJR5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Locates to punctate spots. |
| Tissue Expression | Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | subcellular location:Locates to punctate spots.,subunit:Interacts with PRKACA.,tissue specificity:Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain., |
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