SKU: WP11255 Categories: ,

BCA3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11255-100
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Product details

Background:

This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],

Specifications

Size50μL/100μL
TargetBCA3
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)26kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human BCA3. AA range:111-160
SpecificityBCA3 Polyclonal Antibody detects endogenous levels of BCA3 protein.
Gene NameAKIP1
Protein NameA-kinase-interacting protein 1
Other NameAKIP1; / BCA3; / C11orf17; / A-kinase-interacting protein 1; / Breast cancer-associated gene 3 protein; / PKA-interacting protein; / Proline-rich protein BCA3
SpeciesHuman
Gene ID56672
UniprotQ9NQ31,
Species.1Mouse
Gene ID.1
Uniprot.1Q9JJR5
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Locates to punctate spots.
Tissue ExpressionExpressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.
Signaling_pathway
Research Areas
Functionsubcellular location:Locates to punctate spots.,subunit:Interacts with PRKACA.,tissue specificity:Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.,
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