BHLHA15 rabbit pAb
Ucallm_WP8115-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | BHLHA15 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 21kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human BHLHA15 |
| Specificity | This antibody detects endogenous levels of BHLHA15 at Human, Mouse,Rat |
| Gene Name | BHLHA15 BHLHB8 MIST1 |
| Protein Name | Class A basic helix-loop-helix protein 15 (bHLHa15) (Class B basic helix-loop-helix protein 8) (bHLHb8) (Muscle, intestine and stomach expression 1) (MIST-1) |
| Other Name | |
| Species | Human |
| Gene ID | 168620 |
| Uniprot | Q7RTS1, |
| Species.1 | Mouse |
| Gene ID.1 | 17341 |
| Uniprot.1 | Q9QYC3, |
| Species.2 | Rat |
| Gene ID.2 | 25334 |
| Uniprot.2 | P70562 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in brain, liver, spleen and skeletal muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity). |
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