Price range: $268.00 through $328.00
Background:
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | BIN3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 28kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human BIN3 AA range: 184-234 |
| Specificity | This antibody detects endogenous levels of BIN3 at Human/Mouse/Rat |
| Gene Name | BIN3 |
| Protein Name | BIN3 |
| Other Name | |
| Species | Human |
| Gene ID | 55909 |
| Uniprot | Q9NQY0, |
| Species.1 | Mouse |
| Gene ID.1 | 57784 |
| Uniprot.1 | Q9JI08, |
| Species.2 | Rat |
| Gene ID.2 | 361065 |
| Uniprot.2 | Q68FW8 |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Tissue Expression | Ubiquitously expressed except in brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Involved in cytokinesis and septation where it has a role in the localization of F-actin.,similarity:Contains 1 BAR domain.,tissue specificity:Ubiquitously expressed except in brain., |
