SKU: WM1142 Categories: ,

C-Fos [PTR1390] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1142-50
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Product details

Background:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008],

Specifications

Specification50μL;100μL
Targetc-Fos
ReactivityHuman, Mouse, Rat
ApplicationsWB, IF, ELISA
MW(Calculated)40kD
MW(Observed)62kD
Host SpeciesMouse
Isotype
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
CompositionPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification ProcessThe antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Puity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberPTR1390
ImmunogenAA range: 200-300
Sequence
SpecificityThis antibody detects endogenous levels of C-Fos protein.
Gene NameFOS
Protein NameProto-oncogene c-Fos
AliasFOS;G0S7;Proto-oncogene c-Fos;Cellular oncogene fos;G0/G1 switch regulatory protein 7
Organism-1Human
Gene ID-12353
SwissProt-1P01100
Organism-2Mouse
Gene ID-214281
SwissProt-2P01101
Organism-3Rat
Gene ID-3140675
SwissProt-3P12841
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationNucleus, Cytoplasm
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