SKU: WP8169 Categories: ,

C10orf46 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8169-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetCACUL1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)41kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human C10orf46
SpecificityThis antibody detects endogenous levels of C10orf46 at Human, Mouse,Rat
Gene NameCACUL1 C10orf46 CAC1
Protein NameCDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin1)
Other Name
SpeciesHuman
Gene ID143384
UniprotQ86Y37,
Species.1Mouse
Gene ID.178832
Uniprot.1Q8R0X2,
Species.2Rat
Gene ID.2365493
Uniprot.2Q5XI53
Cellular Localization
Tissue ExpressionUbiquitously expressed with highest expression in the mammary gland and large intestine. Highly expressed in cancer tissues and cancer cell lines. During cell cycle progression expression is high in G1/S, low in the middle of S phase, and increases again in S/G2 phase.
Signaling_pathway
Research Areas
FunctionCell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition.
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