Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C10orf46
Specificity
This antibody detects endogenous levels of C10orf46 at Human, Mouse,Rat
Gene Name
CACUL1 C10orf46 CAC1
Protein Name
CDK2-associated and cullin domain-containing protein 1 (Cdk-associated cullin1)
Other Name
Species
Human
Gene ID
143384
Uniprot
Q86Y37,
Species.1
Mouse
Gene ID.1
78832
Uniprot.1
Q8R0X2,
Species.2
Rat
Gene ID.2
365493
Uniprot.2
Q5XI53
Cellular Localization
Tissue Expression
Ubiquitously expressed with highest expression in the mammary gland and large intestine. Highly expressed in cancer tissues and cancer cell lines. During cell cycle progression expression is high in G1/S, low in the middle of S phase, and increases again in S/G2 phase.
Signaling_pathway
Research Areas
Function
Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition.