C10orf58 rabbit pAb
Ucallm_WP8107-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | PRXL2A |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 25kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C10orf58 |
| Specificity | This antibody detects endogenous levels of C10orf58 at Human, Mouse,Rat |
| Gene Name | FAM213A C10orf58 PAMM PRO2290 PSEC0139 UNQ611/PRO1198 |
| Protein Name | Redox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) |
| Other Name | |
| Species | Human |
| Gene ID | 84293 |
| Uniprot | Q9BRX8, |
| Species.1 | Mouse |
| Gene ID.1 | 70564 |
| Uniprot.1 | Q9CYH2, |
| Species.2 | Rat |
| Gene ID.2 | 361118 |
| Uniprot.2 | Q6AXX6 |
| Cellular Localization | Cytoplasm . Secreted . Secreted from mature adipocytes but not from preadipocytes. . |
| Tissue Expression | Expressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs). |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in redox regulation of the cell . Acts as an antioxidant . Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation . May affect bone resorption and help to maintain bone mass . Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway . |
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