Product details
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C4BPA rabbit pAb
Ucallm_WP6886-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | C4BPA |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 66kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C4BPA |
| Specificity | This antibody detects endogenous levels of C4BPA at Human, Mouse,Rat |
| Gene Name | C4BPA C4BP |
| Protein Name | C4b-binding protein alpha chain (C4bp) (Proline-rich protein) (PRP) |
| Other Name | |
| Species | Human |
| Gene ID | 722 |
| Uniprot | P04003, |
| Species.1 | Mouse |
| Gene ID.1 | 12269 |
| Uniprot.1 | P08607, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q63514 |
| Cellular Localization | Secreted. |
| Tissue Expression | Chylomicrons in the plasma. |
| Signaling_pathway | Organismal Systems >> Immune system >> Complement and coagulation cascades |
| Research Areas | |
| Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
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