Product details
Background:
C7orf47 rabbit pAb
Ucallm_WP7106-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | PPP1R35 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 28kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C7orf47 |
| Specificity | This antibody detects endogenous levels of C7orf47 at Human, Mouse |
| Gene Name | PPP1R35 C7orf47 |
| Protein Name | Protein phosphatase 1 regulatory subunit 35 |
| Other Name | |
| Species | Human |
| Gene ID | 221908 |
| Uniprot | Q8TAP8, |
| Species.1 | Mouse |
| Gene ID.1 | 69871 |
| Uniprot.1 | Q9D8C8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel (PubMed:30168418, PubMed:30230954). Co-localizes with RTTN at the centriole (PubMed:30168418). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with RTTN, leading to the centriole to centrosome conversion . In addition, may play a role in the primary cilia assembly (By similarity). |
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