Calretinin Mouse mAb [Mix-mA]
Ucallm_WM1091-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
Specifications
| Size | 50μL/100μL |
| Target | Calretinin |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| MW(Calculated) | |
| MW(Observed) | 32kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Monoclonal |
| Clone Number | 9E7 |
| Immunogen | Synthesized peptide derived from human Calretinin |
| Specificity | This antibody detects endogenous levels of Calretinin at Human, Mouse,Rat |
| Gene Name | CALB2 CAB29 |
| Protein Name | Calretinin |
| Other Name | Calretinin; / CR; / 29 kDa calbindin |
| Species | Human |
| Gene ID | 794 |
| Uniprot | P22676, |
| Species.1 | Mouse |
| Gene ID.1 | 12308 |
| Uniprot.1 | Q08331, |
| Species.2 | Rat |
| Gene ID.2 | 117059 |
| Uniprot.2 | P47728 |
| Cellular Localization | nucleus,cytoplasm,cytosol,gap junction,neuron projection,terminal bouton,synapse, |
| Tissue Expression | Brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Calretinin is a calcium-binding protein which is abundant in auditory neurons.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 6 EF-hand domains.,tissue specificity:Brain., |
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