Product details
Background:
PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008],
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CaMKIβ Polyclonal Antibody
Ucallm_WP11400-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CaMKIβ |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 38kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CaMK1-beta. AA range:161-210 |
| Specificity | CaMKIβ Polyclonal Antibody detects endogenous levels of CaMKIβ protein. |
| Gene Name | PNCK |
| Protein Name | Calcium/calmodulin-dependent protein kinase type 1B |
| Other Name | PNCK; / Calcium/calmodulin-dependent protein kinase type 1B; / CaM kinase I beta; / CaM kinase IB; / CaM-KI beta; / CaMKI-beta; / Pregnancy up-regulated non-ubiquitously-expressed CaM kinase |
| Species | Human |
| Gene ID | 139728 |
| Uniprot | Q6P2M8, |
| Species.1 | Mouse |
| Gene ID.1 | 93843 |
| Uniprot.1 | Q9QYK9, |
| Species.2 | Rat |
| Gene ID.2 | 29660 |
| Uniprot.2 | O70150 |
| Cellular Localization | Cytoplasm . Nucleus . |
| Tissue Expression | Brain,Liver,Placenta,Thalamus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by Ca(2+)/calmodulin.,Function:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.,PTM:Phosphorylated by CAMKK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain., |
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