Price range: $268.00 through $328.00
Background:
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012],
| Size | 50μL/100μL |
| Target | CAN13 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 73kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CAN13 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CAPN13 |
| Protein Name | Calpain-13 (Calcium-activated neutral proteinase 13) (CANP 13) |
| Other Name | |
| Species | Human |
| Gene ID | 92291 |
| Uniprot | Q6MZZ7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q3UW68, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q5BK10 |
| Cellular Localization | intracellular,cytoplasm, |
| Tissue Expression | Weakly expressed in lung and testis. Weakly or not expressed in other tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:It is unlikely that this protein binds calcium as none of the 2 EF-hand domains seem to contain a canonical calcium-binding site.,Function:Probable non-lysosomal thiol-protease.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 2 EF-hand domains.,tissue specificity:Weakly expressed in lung and testis. Weakly or not expressed in other tissues., |
