Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human CAPG
Specificity
This antibody detects endogenous levels of CAPG at Human,Rat
Gene Name
CAPG AFCP MCP
Protein Name
Macrophage-capping protein (Actin regulatory protein CAP-G)
Other Name
Species
Human
Gene ID
822
Uniprot
P40121,
Species.1
Mouse
Gene ID.1
Uniprot.1
P24452,
Species.2
Rat
Gene ID.2
297339
Uniprot.2
Q6AYC4
Cellular Localization
Nucleus . Cytoplasm . Melanosome . Cell projection, lamellipodium . Cell projection, ruffle . In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia. .
Tissue Expression
Macrophages and macrophage-like cells.
Signaling_pathway
Research Areas
Function
Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.