Product details
Background:
CAPRIN2 rabbit pAb
Ucallm_WP6924-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CAPRIN2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 124kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CAPRIN2 |
| Specificity | This antibody detects endogenous levels of CAPRIN2 at Human, Mouse |
| Gene Name | CAPRIN2 C1QDC1 EEG1 KIAA1873 RNG140 |
| Protein Name | Caprin-2 (C1q domain-containing protein 1) (Cytoplasmic activation/proliferation-associated protein 2) (Gastric cancer multidrug resistance-associated protein) (Protein EEG-1) (RNA granule protein 140) |
| Other Name | |
| Species | Human |
| Gene ID | 65981 |
| Uniprot | Q6IMN6, |
| Species.1 | Mouse |
| Gene ID.1 | 232560 |
| Uniprot.1 | Q05A80 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cytoplasm.; [Isoform 2]: Mitochondrion. Cytoplasm. Expressed throughout the cytoplasm.; [Isoform 5]: Mitochondrion. Colocalizes with aggregated mitochondria.; Cell membrane; Peripheral membrane protein . |
| Tissue Expression | Detected in all tissues tested with highest levels of expression in brain and spleen. |
| Signaling_pathway | |
| Research Areas | |
| Function | Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway . Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling . May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation . May be involved in apoptosis . |
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