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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/CASS4 Polyclonal Antibody
SKU: WP3195 Categories: ,

CASS4 Polyclonal Antibody

Ucallm_WP3195-50

Price range: $268.00 through $328.00

SKU: WP3195-100
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Product details

Background:

alternative products:Experimental confirmation may be lacking for some isoforms, function:Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading., PTM:Phosphorylated on tyrosines by SRC., similarity:Belongs to the CAS family., similarity:Contains 1 SH3 domain., subunit:Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus)., tissue specificity:Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.,

Specifications

Size50μL/100μL
TargetCASS4
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)86kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein AA range: 302-352
SpecificityCASS4 Polyclonal Antibody detects endogenous levels of protein.
Gene NameCASS4 C20orf32 HEFL
Protein NameCas scaffolding protein family member 4 (HEF-like protein) (HEF1-EFS-p130Cas-like protein) (HEPL)
Other Name
SpeciesHuman
Gene ID57091
UniprotQ9NQ75,
Species.1Mouse
Gene ID.1
Uniprot.1Q08EC4
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton . Cell junction, focal adhesion .
Tissue ExpressionExpressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.
Signaling_pathway
Research Areas
FunctionAlternative products:Experimental confirmation may be lacking for some isoforms,Function:Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.,PTM:Phosphorylated on tyrosines by SRC.,similarity:Belongs to the CAS family.,similarity:Contains 1 SH3 domain.,subunit:Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus).,tissue specificity:Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.,
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