CATK (Cleaved-Ala115) rabbit pAb
Ucallm_WP0113-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | CATK |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 23kD,37kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CATK (Cleaved-Ala115) |
| Specificity | This antibody detects endogenous levels of Human,Mouse,Rat CATK (Cleaved-Ala115, protein was cleaved amino acid sequence between 114-115 ) |
| Gene Name | CTSK CTSO CTSO2 |
| Protein Name | CATK (Cleaved-Ala115) |
| Other Name | Cathepsin K; / Cathepsin O; / Cathepsin O2; / Cathepsin X |
| Species | Human |
| Gene ID | 1513 |
| Uniprot | P43235, |
| Species.1 | Mouse |
| Gene ID.1 | 13038 |
| Uniprot.1 | P55097, |
| Species.2 | Rat |
| Gene ID.2 | 29175 |
| Uniprot.2 | O35186 |
| Cellular Localization | Lysosome . Secreted . Apical cell membrane; Peripheral membrane protein; Extracellular side . Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells. . |
| Tissue Expression | Predominantly expressed in osteoclasts (bones) (PubMed:7805878). Expressed in thyroid epithelial cells (PubMed:11082042). |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Lysosome;Cellular Processes >> Cell growth and death >> Apoptosis;Organismal Systems >> Immune system >> Toll-like receptor signaling pathway;Organismal Systems >> Development and regeneration >> Osteoclast differentiation;Human Diseases >> Immune disease >> Rheumatoid arthritis |
| Research Areas | >>Lysosome; / >>Apoptosis; / >>Osteoclast differentiation; / >>Toll-like receptor signaling pathway; / >>Rheumatoid arthritis |
| Function |
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