Price range: $268.00 through $328.00
Background:
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | CBPB1 |
| Reactivity | Human, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CBPB1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CPB1 CPB PCPB |
| Protein Name | Carboxypeptidase B (Pancreas-specific protein) (PASP) |
| Other Name | |
| Species | Human |
| Gene ID | 1360 |
| Uniprot | P15086, |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P19223 |
| Cellular Localization | Secreted . Zymogen granule lumen . |
| Tissue Expression | Pancreas. |
| Signaling_pathway | |
| Research Areas | >>Pancreatic secretion; / >>Protein digestion and absorption |
| Function | Catalytic activity:Preferential release of a C-terminal lysine or arginine amino acid.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Pancreas., |
