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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/CBPD Polyclonal Antibody
SKU: WP0981 Categories: ,

CBPD Polyclonal Antibody

Ucallm_WP0981-50

Price range: $268.00 through $328.00

SKU: WP0981-100
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Product details

Background:

carboxypeptidase D(CPD) Homo sapiens The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCBPD
ReactivityHuman, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)151kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityCBPD Polyclonal Antibody detects endogenous levels of protein.
Gene NameCPD
Protein NameCarboxypeptidase D (Metallocarboxypeptidase D) (gp180)
Other Name
SpeciesHuman
Gene ID1362
UniprotO75976,
Species.1Mouse
Gene ID.1
Uniprot.1O89001,
Species.2Rat
Gene ID.2
Uniprot.2Q9JHW1
Cellular LocalizationCell membrane; Single-pass type I membrane protein .
Tissue ExpressionHighly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines.
Signaling_pathway
Research Areas
FunctionCatalytic activity:Releases C-terminal Arg and Lys from polypeptides.,cofactor:Binds 2 zinc ions per subunit.,Domain:There are 3 carboxypeptidase-like domains. Only the first two domains seem to have kept a catalytic activity.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines.,
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