Product details
Background:
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CCDC65 rabbit pAb
Ucallm_WP8823-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CCDC65 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 53kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CCDC65 |
| Specificity | This antibody detects endogenous levels of CCDC65 at Human, Mouse,Rat |
| Gene Name | CCDC65 |
| Protein Name | Coiled-coil domain-containing protein 65 (Testis development protein NYD-SP28) |
| Other Name | |
| Species | Human |
| Gene ID | 85478 |
| Uniprot | Q8IXS2, |
| Species.1 | Mouse |
| Gene ID.1 | 105833 |
| Uniprot.1 | Q8VHI7, |
| Species.2 | Rat |
| Gene ID.2 | 362994 |
| Uniprot.2 | Q5XIJ8 |
| Cellular Localization | Cytoplasm, cytoskeleton, flagellum basal body . Cell projection, cilium, flagellum . Cytoplasm, cytoskeleton, flagellum axoneme . |
| Tissue Expression | Highly expressed in adult testis, in spermatocytes and spermatids. Also observed in spermatogonia. Not detected in Leydig cells, nor in fetal testis (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules . |
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