CCL1 Polyclonal Antibody
Ucallm_WP1737-50
Price range: $268.00 through $328.00
Product details
Background:
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014],
Specifications
| Size | 50μL/100μL |
| Target | CCL1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 10kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 20-100 |
| Specificity | CCL1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | CCL1 SCYA1 |
| Protein Name | C-C motif chemokine 1 (Small-inducible cytokine A1) (T lymphocyte-secreted protein I-309) |
| Other Name | |
| Species | Human |
| Gene ID | 6346 |
| Uniprot | P22362, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P10146 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted. |
| Tissue Expression | Brain, |
| Signaling_pathway | Organismal Systems >> Immune system >> Chemokine signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor |
| Research Areas | >>Cytokine-cytokine receptor interaction; / >>Viral protein interaction with cytokine and cytokine receptor; / >>Chemokine signaling pathway |
| Function | Function:Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.,induction:By PMA.,online information:CCL1 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer., |
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