SKU: WP1741 Categories: ,

CCL25 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1741-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

Specifications

Size50μL/100μL
TargetCCL25
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)16kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 30-110
SpecificityCCL25 Polyclonal Antibody detects endogenous levels of protein.
Gene NameCCL25 SCYA25 TECK
Protein NameC-C motif chemokine 25 (Chemokine TECK) (Small-inducible cytokine A25) (Thymus-expressed chemokine)
Other Name
SpeciesHuman
Gene ID6370
UniprotO15444,
Species.1Mouse
Gene ID.1
Uniprot.1O35903
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue ExpressionSpecifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Signaling_pathwayOrganismal Systems >> Immune system >> Intestinal immune network for IgA production;Organismal Systems >> Immune system >> Chemokine signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Research Areas>>Cytokine-cytokine receptor interaction; / >>Viral protein interaction with cytokine and cytokine receptor; / >>Chemokine signaling pathway; / >>Intestinal immune network for IgA production
FunctionFunction:Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1.,online information:CCL25 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.,
Please login to post questions
Back to Top
Product has been added to your cart