Product details
Background:
CCM2 rabbit pAb
Ucallm_WP7473-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CCM2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 49kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CCM2 |
| Specificity | This antibody detects endogenous levels of CCM2 at Human, Mouse |
| Gene Name | CCM2 C7orf22 PP10187 |
| Protein Name | Malcavernin (Cerebral cavernous malformations 2 protein) |
| Other Name | |
| Species | Human |
| Gene ID | 83605 |
| Uniprot | Q9BSQ5, |
| Species.1 | Mouse |
| Gene ID.1 | 216527 |
| Uniprot.1 | Q8K2Y9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Cellular community - eukaryotes >> Adherens junction |
| Research Areas | |
| Function | Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity). |
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