Name: CCNL2 Polyclonal Antibody
SKU: WP1983
Price: 268 USD
Availability: InStock

CCNL2 Polyclonal Antibody

Ucallm_WP1983-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP1983-100

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Product details

Background:

The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],

Specifications

Size	50μL/100μL
Target	CCNL2
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	57kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 400-480
Specificity	CCNL2 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	CCNL2 SB138
Protein Name	Cyclin-L2 (Paneth cell-enhanced expression protein)
Other Name
Species	Human
Gene ID	81669
Uniprot	Q96S94,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q9JJA7,
Species.2	Rat
Gene ID.2
Uniprot.2	Q5I0H5
Cellular Localization	Nucleus speckle . Nucleus, nucleoplasm .
Tissue Expression	Widely expressed.
Signaling_pathway
Research Areas
Function	Caution:It is uncertain whether Met-1 or Met-6 is the initiator.,Domain:Contains a RS region (arginine-serine dipeptide repeat) within the C-terminal domain which is the hallmark of the SR family of splicing factors. This region probably plays a role in protein-protein interactions.,Function:Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.,Function:Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis.,induction:By interleukin-2.,online information:CC chemokine receptors entry,similarity:Belongs to the cyclin family. Cyclin L subfamily.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with CDC2L1 or CDC2L2, SFRS2, SFRS7 and POLR2A, the hyperphosphorylated C-terminal domain (CTD) of RNA polymerase II.,tissue specificity:Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.,tissue specificity:Ubiquitously expressed, with a higher expression level observed in ovary, heart, liver and pancreas.,

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CCNL2 Polyclonal Antibody

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CCNL2 Polyclonal Antibody

Product details

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