Product details
Background:
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TP53RK rabbit pAb
Ucallm_WP7566-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TP53RK |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 28kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TP53RK |
| Specificity | This antibody detects endogenous levels of TP53RK at Human, Mouse |
| Gene Name | TP53RK C20orf64 PRPK |
| Protein Name | TP53-regulating kinase (Nori-2) (p53-related protein kinase) |
| Other Name | |
| Species | Human |
| Gene ID | 112858 |
| Uniprot | Q96S44, |
| Species.1 | Mouse |
| Gene ID.1 | 76367 |
| Uniprot.1 | Q99PW4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . |
| Tissue Expression | Highly expressed in testis. Weakly expressed in heart kidney and spleen. |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine . The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 . TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation . |
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