Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human CCPG1
Specificity
This antibody detects endogenous levels of CCPG1 at Human, Mouse
Gene Name
CCPG1 CCP8 CPR8 KIAA1254
Protein Name
Cell cycle progression protein 1 (Cell cycle progression restoration protein 8)
Other Name
Species
Human
Gene ID
9236
Uniprot
Q9ULG6,
Species.1
Mouse
Gene ID.1
72278
Uniprot.1
Q640L3
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasmic granule membrane; Single-pass type II membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
Function
Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation.