CD100 Polyclonal Antibody
Product details
Background:
function:May play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro., similarity:Belongs to the semaphorin family., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 1 PSI domain., similarity:Contains 1 Sema domain., subunit:Homodimer. Binds PLXNB1., tissue specificity:Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.,
Specifications
| Size | 50μL/100μL |
| Target | CD100 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 95kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human SEMA4D. AA range:61-110 |
| Specificity | CD100 Polyclonal Antibody detects endogenous levels of CD100 protein. |
| Gene Name | SEMA4D |
| Protein Name | Semaphorin-4D |
| Other Name | SEMA4D; / C9orf164; / CD100; / SEMAJ; / Semaphorin-4D; / A8; / BB18; / GR3; / CD100 |
| Species | Human |
| Gene ID | 10507 |
| Uniprot | Q92854, |
| Species.1 | Mouse |
| Gene ID.1 | 20354 |
| Uniprot.1 | O09126 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . |
| Tissue Expression | Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver. |
| Signaling_pathway | |
| Research Areas | >>Axon guidance |
| Function | Function:May play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,subunit:Homodimer. Binds PLXNB1.,tissue specificity:Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver., |
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