Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | LAMP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 120kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human LAMP1. AA range:211-260 |
| Specificity | LAMP1 Polyclonal Antibody detects endogenous levels of LAMP1 protein. |
| Gene Name | LAMP1 |
| Protein Name | Lysosome-associated membrane glycoprotein 1 |
| Other Name | LAMP1; / Lysosome-associated membrane glycoprotein 1; / LAMP-1; / Lysosome-associated membrane protein 1; / CD107 antigen-like family member A; / CD107a |
| Species | Human |
| Gene ID | 3916 |
| Uniprot | P11279, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P11438, |
| Species.2 | Rat |
| Gene ID.2 | 25328 |
| Uniprot.2 | P14562 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane; Single-pass type I membrane protein . Late endosome membrane; Single-pass type I membrane protein . Cytolytic granule membrane; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). . |
| Tissue Expression | Brain,Liver,Pancreas,Placenta,Plasma,Testis, |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Transport and catabolism >> Lysosome;Cellular Processes >> Transport and catabolism >> Autophagy - animal |
| Research Areas | >>Autophagy - animal; / >>Lysosome; / >>Phagosome; / >>Tuberculosis |
| Function | Function:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane., |
