Name: U-Blot® PROX1 Rabbit mAb
SKU: WR5111
Price: 268 USD
Availability: InStock

U-Blot® PROX1 Rabbit mAb

Ucallm_WR5111-50

Price range: $268.00 through $328.00

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50μl

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SKU: WR5111-50

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Product details

Background:The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],

Specifications

Size	50μL/100μL
Target	PROX1
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)	83kD
MW(Observed)	83kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:100-1:500; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM1306R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	PROX1
Protein Name	Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)
Other Name
Species	Human
Gene ID	5629
Uniprot	Q92786,
Species.1	Mouse
Gene ID.1
Uniprot.1	P48437
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus . RORG promotes its nuclear localization. .
Tissue Expression	Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.
Signaling_pathway
Research Areas
Function	Function:May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons.,similarity:Belongs to the Prospero homeobox family.,similarity:Contains 1 Prospero-type homeobox DNA-binding domain.,tissue specificity:Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.,

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U-Blot® PROX1 Rabbit mAb

Product details

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U-Blot® PROX1 Rabbit mAb

Product details

Specifications

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