SKU: WP15335 Categories: ,

CD248 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15335-100
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Product details

Background:

function:May play a role in tumor angiogenesis., online information:Endosialin, PTM:May be N-glycosylated., PTM:O-glycosylated with sialylated oligosaccharides., similarity:Contains 1 C-type lectin domain., similarity:Contains 1 EGF-like domain., similarity:Contains 1 Sushi (CCP/SCR) domain., tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.,

Specifications

Size50μL/100μL
TargetCD248
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)80kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CD248. AA range:341-390
SpecificityCD248 Polyclonal Antibody detects endogenous levels of CD248 protein.
Gene NameCD248
Protein NameEndosialin
Other NameCD248; / CD164L1; / TEM1; / Endosialin; / Tumor endothelial marker 1; / CD248
SpeciesHuman
Gene ID57124
UniprotQ9HCU0,
Species.1Mouse
Gene ID.1
Uniprot.1Q91V98
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Single-pass type I membrane protein .
Tissue ExpressionExpressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
Signaling_pathway
Research Areas
FunctionFunction:May play a role in tumor angiogenesis.,online information:Endosialin,PTM:May be N-glycosylated.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.,
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